Neighborhood Health Care Inc. (NHC) is a project with a history of over 33 years of Section 330 funding. Formerly part of the Cincinnati Health Network, Neighborhood Health Care, Inc. was separated from the Network at the request of the BPHC in February 2003, creating a standalone grantee with a unique composition. With the assistance of BPHC, Neighborhood Health Care, Inc. became a grantee with two sub-grantees; Crossroad, a private, nonprofit, faith-based organization that that operates Crossroad Health Center (with a fully compliant 330 board of directors, sliding fee scale, and FTCA coverage), and the Elm Street Health Center, one of five clinics operated by the City of Cincinnati's Health Department.

Neighborhood Health Care, Inc. operates seven separate clinical sites: Mt. Auburn Health Center, East End Health Center, and the Walnut Hills/Evanston Health Center, and four school-based clinics: Taft Elementary School, Rockdale Academy, Burton Elementary School and South Avondale Elementary School. These seven sites are located in Hamilton County, Ohio within the City of Cincinnati, serving five neighborhoods Mt. Auburn, East End, Walnut Hills, Evanston and Avondale. Neighborhood Health Care, Inc. receives both Section 330e and School-Based Health Center (Health Schools Healthy Communities) funding.

Since separating from Cincinnati Health Network, Neighborhood Health Care, Inc. has worked to identify and reduce administrative and operational overlap, reducing costs among the community health centers by over $750,000. Neighborhood Health Care, Inc. participates in Ohio Shared Information Services (OSIS, a BPHC SIMIS project), which provides billing, quality assurance and other shared services. Neighborhood Health Care, Inc. also operates the MedShare Pharmacy, which provides pharmaceuticals to low income patients at over forty satellite health center sites throughout Ohio and Northern Kentucky via a courier and commercial delivery service system. The target population is low-income (<200% of FPL), uninsured, Medicaid and Medicare recipients, and underinsured individuals in their service area.